MESO BOTO-Xtreme+ (

Targeted and result-oriented alternative to Botox) (10 ml)

MESO BOTO-Xtreme⁺ is a meso treatment that restructures and tightens the skin. It is designed to work from within to restore the skin's beautiful appearance.

With a unique combination of argireline, SNAP-8, leuphasyl, hyaluronic acid, and retinolMESO BOTO-Xtreme⁺ is an ideal solution for treating wrinkles, and the product is a good alternative to botox if you want to avoid side effects.

Although MESO BOTO-Xtreme⁺ does not have the side effects of botox, the treatment has the same relaxing effect on the facial muscles and fibroblasts.

Additionally, the product provides antioxidation and nourishment.

The treatment revitalizes and hydrates tired or worn-out skin, treats wrinkles, and restores density in mature or loose skin. Therefore, it has an effective tightening effect, smooths out fine wrinkles, and gives the skin a strong, elastic appearance.
 

Remove wrinkles under the eyes with MESO BOTO-Xtreme⁺

With MESO BOTO-Xtreme⁺, you can remove wrinkles under the eyes and reduce skin laxity. MESO BOTO-Xtreme⁺ is a meso treatment designed to rebuild and tighten the skin from the deep layers. The treatment tightens and moisturizes the skin deeply and removes neck folds, skin laxity, and wrinkles under the eyes.

The combination of mimetic peptides such as argireline, SNAP-8, and leuphasyl, along with ingredients like hyaluronic acid and retinol, has a remarkable effect, smoothing out fine lines and giving the skin a firm and even appearance.

Target the first signs of aging

The treatment contains active ingredients that specifically target the main causes of the first signs of aging in the skin - with documented effect.

MESO BOTO-Xtreme⁺ has a similar effect to botulinum toxin used in botox treatments, but without the side effects known from botox treatment. MESO BOTO-Xtreme⁺ relaxes the facial muscles and fibroblasts, and the tightening and nourishing ingredients reduce wrinkles under the eyes, decrease neck folds, and give the skin a healthy, youthful appearance.

How the treatment works

MESO BOTO-Xtreme⁺ tones the facial muscles by inhibiting the neurons that control the nerves, which is crucial for the smoothing effect the treatment has on the skin.

The muscles receive neurotransmitters that are transported inside the vesicle, causing them to contract. Before the vesicle releases its signaling molecules, a kind of protein hinges between the vesicle's and the cell's membrane is formed, called the SNARE complex. 

The SNARE protein complex is crucial for the release of neurotransmitters at the synapse, which is the contact point between two nerve cells. The protein complex consists of 3 structures: VAMP, syntaxin, and SNAP 25. The connection between the vesicle and the complex is necessary for fusion with the neuron membrane, and this is how the neurotransmitter acetylcholine is released.

Effective like botox - without side effects

Weakening the SNARE complex causes muscle relaxation, but with MESO BOTO-Xtreme⁺, the mimetic peptides only slightly affect the complex as they act through the SNAP 25 protein.

In contrast, botulinum acts irreversibly and destructively, and the synaptic vesicles cannot anchor and release acetylcholine. With MESO BOTO-Xtreme⁺, they can, allowing for neurotransmission as the muscles relax. The process has a smoothing effect on muscle contraction and prevents wrinkled skin.

Due to its ingredient composition, MESO BOTO-Xtreme⁺ provides intense revitalization and hydration to tired or loose skin.

The treatment removes wrinkles under the eyes and tightens mature or loose skin, resulting in a beautiful, healthy appearance.

The product should not be used during pregnancy and breastfeeding.

MESO BOTO-Xtreme⁺10 ml.

• For 10 - 20 treatments

• 10 x sterile syringes (For extraction of the product from a sterile vial using the non-invasive method.)

• 10 x sterile hypodermic needles (For extraction of the product from a sterile vial using the non-invasive method.)

DESCRIPTION
MESO BOTO-Xtreme⁺ is a restructuring and tightening facial treatment designed to work deeply within the layers of the skin to restore its good appearance.

The unique combination of mimetic peptides such as Argireline, SNAP-8, and Leuphasyl, along with other ingredients like Hyaluronic acid and Retinol, has a specific effect that smooths fine lines and helps the skin achieve a smoother, better, and more elastic appearance.

The formula contains active ingredients with documented effects, all working together against the primary causes of the first signs of aging.

MESO BOTO-Xtreme⁺ has a similar effect to botulinum (without side effects), resulting in relaxation of facial muscles and fibroblasts, as well as the filling, antioxidant, and nourishing effects provided by the other ingredients.

Regulating muscle tone and inhibiting neuronal activity over the nerves are key factors in achieving the skin-smoothing effect. The muscles contract when they receive a neurotransmitter transported in a vesicle. The SNARE protein complex (SNAP Receptor) is essential for the release of the neurotransmitter under the synapse.

This complex consists of 3 structures: VAMP, Syntaxin & SNAP 25. The fusion of the vesicle and the complex is necessary for binding to the neuron membrane and subsequently releasing the neurotransmitter acetylcholine.

Inhibiting the SNARE complex causes muscle relaxation, but in this case, the mimetic peptides only slightly destabilize the complex by affecting the SNAP 25 protein, rather than destroying it as botulinum does.

In this way, the synaptic vesicles cannot effectively bind and release acetylcholine, allowing for some neurotransmission while the muscles relax. The result is a smoothing of muscle contraction that prevents the appearance of wrinkles.

Ingredients INCI: AQUA, RETINOL, ASCORBIC ACID, PENTAPEPTIDE-3, ACETYL HEXAPEPTIDE-8, ACETYL OCTAPEPTIDE-3, SODIUM HYALURONATE, AVENA SATIVA EXTRACT, ZINC CHLORIDE, COPPER GLUCONATE, COBALT GLUCONATE, ARGININE ASPARTATE, VALINE, PYRIDOXINE, THIAMINE HCL, SODIUM CHLORIDE, SODIUM HYDROXIDE.

Up to 63% less wrinkle depth and a visible improvement in skin appearance.

From the grain of Avena Sativa, which contains between 45 and 50% polysaccharides, beta-glucan is extracted, a high-molecular hydrocolloid with a unique sequence of bonds: the beta-1,3-bonds are located at the fourth or fifth position along the chain of glucose molecules, which are joined together by beta-1,4-bonds.

This three-dimensional structure ensures a pronounced stability of the polymer in water. Like other hydrophilic colloids, beta-glucan has a marked ability to bind water and release it to the outer layer of the epidermis (moisturizing effect), as well as a good protective effect on the skin against irritating chemical and physical substances. Thanks to its high film-forming ability, it also leaves the skin with a pleasantly soft and velvety feeling.

In recent studies, it has also been shown that beta-glucan has an effective inhibitory effect on xanthine oxidase, an endogenous enzyme that can generate hydrogen peroxide and free radicals by converting the substrate xanthine to uric acid:

A concentration of just 0.5% beta-glucan ensured the survival of 100% of cells in cultures of human fibroblasts (skin cells) exposed to the enzyme's action. Among the other compounds in Avena Sativa's phytocomplex, we can also mention avenanthramides, substances whose soothing and anti-itching properties have been proven in vivo, even at very low concentrations on skin exposed to UV radiation.

Avena Sativa is used in various dietary supplements to promote increased libido. Although it has not yet been scientifically proven, Avena Sativa appears to positively affect serum testosterone. Therefore, it is increasingly used in cosmetics to improve skin firmness.