MESO BOTO-X<small>treme<sup>+ (Targeted and effective alternative to Botulinum) (10 ml)

MESO BOTO-Xtreme+ (Targeted and effective alternative to Botulinum) (10 ml)

MESO BOTO-Xtreme+
(also for Non-invasive treatment (not restricted to medical professionals) with, for example, MESO
power Pen or similar.)

1 set includes:

  • 1 x MESO BOTO-Xtreme+ (1 vial of 10 ml) 

  • For 10 - 20 treatments

  • 10 x sterile syringes (For extraction of the product from the sterile vial using the non-invasive method.)

  • 10 x sterile hypodermic needles (For extraction of the product from the sterile vial using the non-invasive method.)


  • Active ingredients: penta-, hexa-, and octapeptides, as well as Avena Sativa and hyaluronic acid (HA)

  • Indication: anti-aging
  • Result: similar botulinum (Botox) effect
  • Effective ingredients: multi-peptides


 

DISCOUNT REGARDLESS OF COCKTAIL TYPE:

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Stock status: In stock
Model/Product no.: MST406

WORLDWIDE SHIPPING

We ship WorldWide every day

Fast delivery WorldWide

If you order before 4pm

Customer service and support

Call us at
(+45) 71741108

Certified products

Produced in the EU

MESO BOTO-Xtreme+


Targeted and result-oriented alternative to Botulinum


 

MAIN TREATMENT AREA

  • Face

  • Neck and double chin

 

TREATMENT PROGRAM:

  1. 1st and 2nd month: 1 weekly session - 4-8 total

  2. 3rd month: 1 session every two weeks - 2 total

  3. Follow-up: 1 session every 3 months - recommended

 

RESULTS

  • Removes or reduces wrinkles under the eyes

  • Eliminates skin laxity

  • Reduces neck folds

  • Moisturizes and strengthens the skin

  • Tightens and lifts the skin


MESO BOTO-Xtreme+
Targeted and result-oriented alternative to Botulinum

Who can perform treatment with MESO BOTO-Xtreme+?

Treatment with MESO BOTO-Xtreme is not restricted to medical professionals when performed using a non-invasive method.

 

This treatment is highly effective as a non-invasive method and can be performed with, for example, MESOpower Pen along with the meso modules MESO 11-Point Micro Module and MESO 3-Point Nano Module. This means that any qualified practitioner, such as cosmetologists, Meso- and PMU artists, etc., can perform the treatment.

 

MESO BOTO-Xtreme+ is a meso treatment that restructures and tightens the skin. It is designed to work from within to restore the skin's beautiful appearance.


With a unique combination of argireline, SNAP-8, leuphasyl, hyaluronic acid, and retinolMESO BOTO-Xtremeis an ideal solution for treating wrinkles, and the product is a good alternative to Botulinum if you want to avoid side effects.


Although MESO BOTO-Xtremedoes not have the side effects of botox, the treatment has the same relaxing effect on the facial muscles and fibroblasts.

Additionally, the product provides antioxidation and nourishment.

 

The treatment revitalizes and hydrates tired or worn-out skin, treats wrinkles, and restores density in mature or loose skin. Therefore, it has an effective tightening effect, smooths out fine wrinkles, and gives the skin a strong, elastic appearance.
 


Remove wrinkles under the eyes with MESO BOTO-Xtreme+

With MESO BOTO-Xtreme+, you can remove wrinkles under the eyes and reduce skin laxity. MESO BOTO-Xtremeis a meso treatment designed to rebuild and tighten the skin from the deep layers. The treatment tightens and moisturizes the skin deeply and removes neck folds, skin laxity, and wrinkles under the eyes.

 

The combination of mimetic peptides such as argireline, SNAP-8, and leuphasyl, along with ingredients like hyaluronic acid and retinol, has a remarkable effect, smoothing out fine lines and giving the skin a firm and even appearance.

Target the first signs of aging

The treatment contains active ingredients that specifically target the main causes of the first signs of aging in the skin - with documented effect.

 

MESO BOTO-Xtremehas a similar effect to botulinum toxin used in botox treatments, but without the side effects known from botox treatment. MESO BOTO-Xtremerelaxes the facial muscles and fibroblasts, and the tightening and nourishing ingredients reduce wrinkles under the eyes, decrease neck folds, and give the skin a healthy, youthful appearance.

 

How the treatment works

MESO BOTO-Xtreme+ tones the facial muscles by inhibiting the neurons that control the nerves, which is crucial for the smoothing effect the treatment has on the skin.

The muscles receive neurotransmitters that are transported inside the vesicle, causing them to contract. Before the vesicle releases its signaling molecules, a kind of protein hinges between the vesicle's and the cell's membrane is formed, called the SNARE complex. 

 

The SNARE protein complex is crucial for the release of neurotransmitters at the synapse, which is the contact point between two nerve cells. The protein complex consists of 3 structures: VAMP, syntaxin, and SNAP 25. The connection between the vesicle and the complex is necessary for fusion with the neuron membrane, and this is how the neurotransmitter acetylcholine is released.

Effective like Botulinum - without side effects

Weakening the SNARE complex causes muscle relaxation, but with MESO BOTO-Xtreme+, the mimetic peptides only slightly affect the complex as they act through the SNAP 25 protein.

 

In contrast, botulinum acts irreversibly and destructively, and the synaptic vesicles cannot anchor and release acetylcholine. With MESO BOTO-Xtreme+, they can, allowing for neurotransmission as the muscles relax. The process has a smoothing effect on muscle contraction and prevents wrinkled skin.

 

Due to its ingredient composition, MESO BOTO-Xtremeprovides intense revitalization and hydration to tired or loose skin.

 

The treatment removes wrinkles under the eyes and tightens mature or loose skin, resulting in a beautiful, healthy appearance.

 

The product should not be used during pregnancy and breastfeeding.

MESO BOTO-Xtreme+10 ml.

  • For 10 - 20 treatments

  • 10 x sterile syringes (For extraction of the product from a sterile vial using the non-invasive method.)

  • 10 x sterile hypodermic needles (For extraction of the product from a sterile vial using the non-invasive method.)

DESCRIPTION
MESO BOTO-Xtremeis a restructuring and tightening facial treatment designed to work deeply within the layers of the skin to restore its good appearance.

 

The unique combination of mimetic peptides such as Argireline, SNAP-8, and Leuphasyl, along with other ingredients like Hyaluronic acid and Retinol, has a specific effect that smooths fine lines and helps the skin achieve a smoother, better, and more elastic appearance.

 

The formula contains active ingredients with documented effects, all working together against the primary causes of the first signs of aging.

 

MESO BOTO-Xtremehas a similar effect to botulinum (without side effects), resulting in relaxation of facial muscles and fibroblasts, as well as the filling, antioxidant, and nourishing effects provided by the other ingredients.

 

Regulating muscle tone and inhibiting neuronal activity over the nerves are key factors in achieving the skin-smoothing effect. The muscles contract when they receive a neurotransmitter transported in a vesicle. The SNARE protein complex (SNAP Receptor) is essential for the release of the neurotransmitter under the synapse.

 

This complex consists of 3 structures: VAMP, Syntaxin & SNAP 25. The fusion of the vesicle and the complex is necessary for binding to the neuron membrane and subsequently releasing the neurotransmitter acetylcholine.

 

Inhibiting the SNARE complex causes muscle relaxation, but in this case, the mimetic peptides only slightly destabilize the complex by affecting the SNAP 25 protein, rather than destroying it as botulinum does.

 

In this way, the synaptic vesicles cannot effectively bind and release acetylcholine, allowing for some neurotransmission while the muscles relax. The result is a smoothing of muscle contraction that prevents the appearance of wrinkles.

Ingredients INCI: AQUA, RETINOL, ASCORBIC ACID, PENTAPEPTIDE-3, ACETYL HEXAPEPTIDE-8, ACETYL OCTAPEPTIDE-3, SODIUM HYALURONATE, AVENA SATIVA EXTRACT, ZINC CHLORIDE, COPPER GLUCONATE, COBALT GLUCONATE, ARGININE ASPARTATE, VALINE, PYRIDOXINE, THIAMINE HCL, SODIUM CHLORIDE, SODIUM HYDROXIDE.

 

Up to 63% less wrinkle depth and a visible improvement in skin appearance.

From the grain of Avena Sativa, which contains between 45 and 50% polysaccharides, beta-glucan is extracted, a high-molecular hydrocolloid with a unique sequence of bonds: the beta-1,3-bonds are located at the fourth or fifth position along the chain of glucose molecules, which are joined together by beta-1,4-bonds.

 

This three-dimensional structure ensures a pronounced stability of the polymer in water. Like other hydrophilic colloids, beta-glucan has a marked ability to bind water and release it to the outer layer of the epidermis (moisturizing effect), as well as a good protective effect on the skin against irritating chemical and physical substances. Thanks to its high film-forming ability, it also leaves the skin with a pleasantly soft and velvety feeling.

 

In recent studies, it has also been shown that beta-glucan has an effective inhibitory effect on xanthine oxidase, an endogenous enzyme that can generate hydrogen peroxide and free radicals by converting the substrate xanthine to uric acid:

 

A concentration of just 0.5% beta-glucan ensured the survival of 100% of cells in cultures of human fibroblasts (skin cells) exposed to the enzyme's action. Among the other compounds in Avena Sativa's phytocomplex, we can also mention avenanthramides, substances whose soothing and anti-itching properties have been proven in vivo, even at very low concentrations on skin exposed to UV radiation.

 

Avena Sativa is used in various dietary supplements to promote increased libido. Although it has not yet been scientifically proven, Avena Sativa appears to positively affect serum testosterone. Therefore, it is increasingly used in cosmetics to improve skin firmness.

 

 

Ingredients 409
Treatment Areas and Results 410
How to use 411

Ingredients and their Functions:

Aqua (Water)

  • Origin: Purified water.
  • Effect: The base of the product, serving as a solvent for active ingredients. Contributes to hydration.

Retinol (Vitamin A)

  • Origin: Synthetic or derived from natural sources such as fish or plants.
  • Effect:
    • Promotes cell renewal, resulting in smoother and more even skin.
    • Reduces the appearance of fine lines and wrinkles.
    • Improves skin texture and reduces pigmentation.

Ascorbic Acid (Vitamin C)

  • Origin: Extracted from citrus fruits or produced synthetically.
  • Effect:
    • Powerful antioxidant that protects against free radicals.
    • Brightens the skin and improves skin tone.
    • Stimulates collagen production and reduces signs of aging.

Pentapeptide-3

  • Origin: Synthetic peptide.
  • Effect:
    • Improves skin firmness and elasticity.
    • Enhances collagen synthesis and reduces wrinkles.

Acetyl Hexapeptide-8

  • Origin: Synthetically produced.
  • Effect:
    • Known as a “Botox-like” peptide.
    • Reduces muscle contractions, thereby diminishing fine lines and wrinkles.

Acetyl Octapeptide-3

  • Origin: Synthetic peptide.
  • Effect:
    • Reduces muscle activity and minimizes the appearance of wrinkles.
    • Supports skin firmness and elasticity.

Sodium Hyaluronate

  • Origin: Derived from hyaluronic acid through fermentation.
  • Effect:
    • Provides intense hydration by attracting moisture to the skin.
    • Plumps the skin, reducing fine lines and imparting a more youthful glow.

Avena Sativa Extract (Oat Extract)

  • Origin: Extracted from oat kernels.
  • Effect:
    • Soothes and calms the skin with anti-inflammatory properties.
    • Reduces irritation and redness.

Zinc Chloride

  • Origin: Chemically produced.
  • Effect:
    • Regulates sebum production and prevents clogged pores.
    • Strengthens the skin’s barrier and protects against environmental damage.

Copper Gluconate

  • Origin: Combination of copper and gluconic acid.
  • Effect:
    • Supports collagen synthesis.
    • Has antioxidant properties that protect the skin from aging.

Cobalt Gluconate

  • Origin: Combination of cobalt and gluconic acid.
  • Effect:
    • Boosts the skin’s energy and metabolism.
    • Contributes to a more radiant complexion.

Arginine Aspartate

  • Origin: Amino acids from plants or synthetically produced.
  • Effect:
    • Promotes skin regeneration and elasticity.
    • Contributes to skin hydration and cell renewal.

Valine

  • Origin: Essential amino acid found in protein-rich foods like beans and grains.
  • Effect:
    • Aids in tissue repair and strengthens the skin’s structure.

Pyridoxine (Vitamin B6)

  • Origin: Found in foods such as fish and bananas, or produced synthetically.
  • Effect:
    • Regulates sebum production and promotes healthy skin.
    • Soothes irritation and reduces acne.

Thiamine HCL (Vitamin B1)

  • Origin: Found in whole grains or synthetically produced.
  • Effect:
    • Protects against oxidative stress and prevents premature aging.
    • Supports the skin’s natural repair processes.

Sodium Chloride

  • Origin: Naturally occurring salt.
  • Effect:
    • Stabilizes the product’s viscosity.
    • Improves the formulation’s stability.

Sodium Hydroxide

  • Origin: Synthetically produced.
  • Effect:
    • Adjusts the pH level to ensure skin tolerance.

Anti-age Properties:
These ingredients work together to hydrate, stimulate collagen production, improve skin elasticity, and protect against oxidative stress, resulting in more youthful, firm, and radiant skin.

 

List of Active Ingredients with their Origin, Effect, and Anti-aging Properties:

Pentapeptides, Hexapeptides, and Octapeptides

  • Origin: Synthetically produced small chains of amino acids.
  • Effect:
    • Reduce fine lines and wrinkles by inhibiting muscle contractions.
    • Improve skin firmness and elasticity by stimulating collagen production.
    • Promote smoother, more youthful-looking skin.

EGF (Epidermal Growth Factor)

  • Origin: Biotechnologically produced protein that mimics the body’s own growth factors.
  • Effect:
    • Stimulates the growth and regeneration of skin cells by binding to epidermal growth factor receptors.
    • Improves cell renewal, healing, and strengthens the skin’s structure.
    • Reduces signs of aging and enhances the skin’s regenerative capacity.

Ferulic Acid

  • Origin: Naturally found in the cell walls of plants such as rice, wheat, and oats.
  • Effect:
    • Powerful antioxidant that protects the skin against oxidative stress and UV damage.
    • Reduces pigmentation and brightens the skin by inhibiting melanin production.

Ubiquinone (Coenzyme Q10)

  • Origin: Naturally occurring antioxidant in the body, also produced synthetically for cosmetics.
  • Effect:
    • Protects the skin from free radicals and environmental damage.
    • Improves the strength and elasticity of cell membranes.
    • Supports cell renewal and reduces visible signs of aging.

Sodium DNA

  • Origin: Extracted from natural sources, often fish DNA.
  • Effect:
    • Deeply moisturizes and promotes cell renewal.
    • Rebuilds connective tissue and strengthens the skin’s structure.
    • Effective for skin healing and regeneration, especially with technologies like mesopen and ultrasound.

Hyaluronic Acid (Sodium Hyaluronate)

  • Origin: Produced through biotechnology, often via bacterial fermentation.
  • Effect:
    • Binds water to the skin, providing intensive moisture.
    • Improves skin volume and elasticity, reducing wrinkles and fine lines.
    • Leaves the skin smooth, plump, and youthful.

Avena Sativa (Oat Extract)

  • Origin: Extracted from oat kernels.
  • Effect:
    • Soothes the skin and reduces inflammation.
    • Protects against environmental damage and strengthens the skin’s natural barrier.
    • Moisturizes and calms irritated skin.

Lecithin, Phytosterols, and Fatty Acids

  • Origin: Extracted from soybeans or sunflower seeds.
  • Effect:
    • Improves the skin’s barrier and reduces moisture loss.
    • Regenerates damaged tissue and strengthens skin elasticity.
    • Supports the skin’s structure, providing a softer, smoother surface.

Anti-aging Properties

These active ingredients work synergistically to:

  • Reduce wrinkles and improve skin elasticity.
  • Protect against free radicals and UV damage.
  • Improve cell renewal and regeneration.
  • Provide intense moisture and strengthen the skin’s barrier, resulting in firm, smooth, and youthful skin.

 

Overall Effect of the Formula

  • Promotes stem cell proliferation and regeneration of damaged tissue.
  • Reduces signs of aging such as wrinkles and fine lines.
  • Improves the skin’s moisture, texture, and appearance.
  • Strengthens the skin’s natural barrier and provides intensive hydration.

These ingredients work synergistically to provide healthy, youthful, and revitalized skin.

Treatment Areas and Results

Treatment Areas:

  • Face:

    • Reduces fine lines and wrinkles.
    • Improves skin firmness and elasticity.
    • Brightens the skin and minimizes pigmentation.
  • Neck:

    • Tightens the skin and reduces visible signs of aging.
    • Gives the skin a more youthful appearance.
  • Décolleté:

    • Enhances skin texture and hydration.
    • Strengthens the skin barrier and reduces dryness.

Results:

  1. Intensive Hydration:

    • Ingredients like Sodium DNA and hyaluronic acid bind moisture to the skin, leaving it smooth and hydrated.
    • Ceramides and squalane help strengthen the skin barrier and retain moisture.
  2. Reduced Aging:

    • EGF (Epidermal Growth Factor): Stimulates cell renewal and regenerates damaged tissue, reducing wrinkles and fine lines.
    • Ferulic Acid: Protects against UV damage and oxidative stress, which accelerates skin aging.
  3. Skin Tightening:

    • Promotes collagen production for firmer and more elastic skin.
    • Strengthens connective tissue and improves skin firmness.
  4. Improved Skin Texture:

    • Ubiquinone (Coenzyme Q10): Enhances elasticity and strengthens cell membranes, creating smoother, more even skin.
    • Brightens the skin by reducing melanin production and evening out pigmentation.
  5. Strengthened Skin Barrier:

    • Ingredients like lecithin, phytosterols, and shea butter help rebuild the skin’s natural protection.
  6. Regeneration of Damaged Tissue:

    • Sodium DNA: Repairs damaged skin cells and promotes healing, improving the skin’s overall health.

Recommendation:

For optimal penetration and maximum results, this treatment can be combined with technologies such as:

  • Electroporation
  • Ultrasound
  • Mesopen or Mesoroller

These technologies enhance the effectiveness of active ingredients by ensuring deeper penetration into the skin.

Step-by-Step Guide for MESO BOTO-Xtreme Treatment

STEP 1: Preparation with MESO PURE PEEL

  1. Prepare the skin thoroughly:

    • Cleanse the treatment area and remove any makeup.
    • Gently apply MESO PURE PEEL to the skin and massage lightly. Do not rinse off.
  2. Active ingredients in MESO PURE PEEL:

    • Lactic Acid, Citric Acid, Malic Acid: Exfoliate and improve skin texture.
    • Bisabolol: Soothes and calms the skin.
    • Citrus Grandis, Vaccinum Myrtillus, and Lemon Peel Extracts: Natural antioxidants that strengthen the skin.

STEP 2: Application of MESO BOTO-Xtreme with Microneedling Modules

  1. Choose the correct needle module:

    • 3-point needle module: For treating thin and visible lines. Work back and forth along the lines using the "press-and-lift" motion.
    • 11-point needle module: For areas with multiple small lines or crepey skin. Work directly on and between the lines using the "press-and-lift" motion.
  2. Settings:

    • Use speed 4-6 and full needle length until micro-bleeding occurs (indicating you are working in the dermis).
  3. Product application:

    • Hold the device in your dominant hand and a 1 ml syringe in the other.
    • Continuously apply small amounts of MESO BOTO-Xtreme during the procedure for optimal penetration.

STEP 3: MESO ANTI-AGE MASK

  1. Apply the mask:

    • Place the transdermal double-layer hydrogel mask on the treated area.
  2. Let the mask work:

    • Leave the mask on for 30 minutes for maximum anti-aging benefits.
    • The active ingredients penetrate deeply into the skin to enhance cell renewal.
  3. Tip:

    • Perform a light massage over the mask during the first 10-15 minutes to improve absorption.

STEP 4: Apply Spheracoll (Vegan Collagen)

  1. After the mask:

    • Remove the mask and evenly apply Spheracoll (1 ball + 2.5 ml activator) to the skin.
    • Massage thoroughly until the product is fully absorbed.
  2. Result:

    • Provides deep hydration, reduces redness, and integrates ingredients into the dermis.

STEP 5: Finish with MESO LIFT AND PROTECT (SPF 50+)

  1. Apply a thin layer:

    • Distribute MESO LIFT AND PROTECT over the treated areas.
  2. Protection:

    • The product offers sun protection and anti-aging benefits for up to 8 hours.
    • Ideal for daily use on dry, sensitive, or photosensitive skin.

Important Notes and Tips

  • Always use the "press-and-lift" technique during microneedling to avoid skin abrasion, scabbing, and hyperpigmentation.
  • Ensure the skin is not dry during the procedure – keep it hydrated with small doses of the product from the syringe.
  • Treatment areas: Forehead, eyes, cheeks, and neck (recommended dose is 0.5 ml per area).

Tip: If you see no redness after the treatment, you should work more intensively on this client next time.


Treatment Program

  1. 1st and 2nd Month:

    • 1 session per week – 4-8 sessions in total.
  2. 3rd Month:

    • 1 session every two weeks – 2 sessions in total.
  3. Follow-up:

    • 1 session every 3 months – recommended to maintain results.

WATCH THE INSTRUCTION VIDEO HERE

Contact
  • mesoskinline
  • juelsmindevej 57
  • 7120 Vejle
  • Denmark
  • Telephone: +4571741108
  • Mobile: +4526361108
  • E-mail:
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  • VAT No:: 39967065
  • Bank details: Sparekassen Kronjylland BIC-kode KRONDK22IBAN- DK9461930013946124
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